Description

Order Diacetylmorphine Hydrochloride (15mg) ONLINE

Indications:Severe chronic pain or pain resistant to other analgesics, in particular pain associated with cancer.

Dosage:Adults:Recommended dosage is one tablet twice daily, at 12-hour intervals.Elderly:As with all narcotics a reduction in dosage may be advisable in the elderly, as appropriate.

Description

Buy diacetylmorphine online
Buy diacetylmorphine online and commonly known by its street names of H, smack, horse, brown, black, tar, and others, is an opioid analgesic originally synthesized by C.R. Alder Wright in 1874 by adding two acetyl groups.
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diacetylmorphine hydrochloride
The hydrochloride salt of a diacetyl derivative of the opiate morphine, a naturally occurring alkaloid extracted from the seedpod of the Asian poppy (Papaver sp.). Once administered, diamorphine (or diacetylmorphine) is rapidly hydrolyzed to 6-monoacetylmorphine (6-MAM) and then to the end-product morphine which binds to opiate receptors located throughout the mammalian nervous and gastrointestinal systems. Inducing a potent analgesia, the use of diamoprhine is often escalated due to a tolerance effect, resulting in abuse that is associated with fatal overdose, abortion, venous sclerosis, and opportunistic infections, among other adverse effects.
Detailed Description:
Background: Heroin dependence (HD) is a chronic relapsing brain disorder that is defined by a compulsion to seek and use heroin, and a loss of control in limiting intake.
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The prescription of diacetylmorphine (heroin) itself for maintenance has become an established treatment in several European countries. However, the neurobiological effects of diacetylmorphine (DAM) on brain function and stress response have not been studied so far. Imaging the acute effects of DAM administration during stress stimuli would elucidate the neurocircuitry and neurobiology of substance use in patients with HD.

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Working hypothesis: The investigators expect that DAM attenuates the engagement of brain regions involved in response inhibition (prefrontal and anterior cingulate cortex), emotional processing (amygdala) and working memory (frontal and mediotemporal cortex). Additionally, we hypothesize that DAM reduces stress response (cortisol, heart rate, skin conductance) to emotional and cognitive stimuli.